Straight answers.
No fluff.

TRT Plus is an iOS and Android app for men on TRT and enhanced athletes. It manages your full protocol — daily dashboard, compound library, dose calculations, injection site rotation, inventory, and reminders — plus AI bloodwork analysis with enhanced reference ranges.

No. TRT Plus is a tracking, modelling, and analytical app — not a medical device and not a clinician. It's designed to help you have better-informed conversations with your healthcare provider and surface insights worth raising. Not every clinic looks beyond the basics, and not everyone has access to premium care. TRT Plus exists to bridge that gap — research-backed information and precision analysis, rather than crowd-sourcing from randoms in Facebook groups. Consult with your healthcare provider before making medical decisions.

TRT Plus is $12.99 USD on the App Store and Google Play.

The right markers avoid unnecessary specialist referrals. Standard panels routinely flag results in men who train as cause for concern — the markers most labs use for liver and kidney function are also released by muscle tissue. A $600 referral to a hepatologist to learn that elevated liver enzymes are normal in anyone who lifts weights was part of the reason TRT Plus was built. The right panel answers that question for free. Running the right bioidentical compounds at an informed dose tends to deliver better outcomes than a commercially driven protocol built around exotic peptides and add-ons you may not need. Understanding what your markers actually show — against reference ranges built for this population — means you can have that conversation from a position of knowledge.

TRT is a game changer. The management side can be a hassle. What to take and when, dialling in, rotating sites, calculating draw volumes, monitoring supplies, scheduling bloodwork. TRT Plus runs all of it in the background: reminders when doses are due, daily tracking so you remember what was taken, dose calcs that update in real time, rotation planned ahead, and inventory management that keeps you ahead of your supplies.

No. TRT Plus does one thing better than any other app — managing TRT and enhanced protocols. Two screens: My Protocol and My Bloodwork. Everything else is noise. If you want a star badge for being a Protocol Pro, this isn't your app.

Built by an engineer on TRT who identified the gap between how TRT is actually managed and what was available to help with it. Input came from TRT clinics, coaches, and pathology partners across multiple regions. The reference ranges are grounded in de-identified patient data from a clinical population of men on TRT — not general health databases. The marker selection came from experience — knowing which panels give athletes the wrong answer, and building something that gives them the right one.

Tap Quick Add and select from a library of 80+ pre-configured compounds covering anabolics, TRT ancillaries, peptides, GLPs, and SARMs. Each comes pre-loaded with a research-backed starting dose, frequency, half-life, and inventory — no manual entry.

Yes. Enter your concentration, frequency, and weekly dose — the app calculates your exact draw volume automatically. Every field updates every other field. Change the volume and the mg recalculates. Change the mg and the volume follows. Change your injection frequency and your weekly total stays locked — only the per-injection volume adjusts. It works in every direction, every time. This is the feature you'll use most. No other TRT app does it this way.

Yes. Set your preferred injection sites once and the Rotation Planner forecasts the sequence so you're not hammering one spot. Sites appear on the Daily Dashboard alongside each due dose, and are abbreviated on the T Fluctuation chart — RD for Right Delt, LV for Left Ventroglute, and so on.

Yes. Medication reminders fire when each compound is due — injectables, orals, peptides, cream. Mark as taken or snooze from your phone or smart watch.

Yes. Inventory management is protocol-aware — it tracks your remaining supply against your dosing schedule and sends advance reorder notifications before you run out. The inventory counter turns amber at four weeks remaining and red at two weeks, giving you a clear visual cue at a glance.

Your full day at a glance — every compound due today with its scheduled time, dose, draw volume, and injection site. Each entry has a checkbox so you can mark doses as taken as you go.

Tap the checkbox next to the compound. You can even mark as taken direct from the notification without opening the app.

The app tracks your schedule against actual doses taken. If a dose goes unmarked, inventory will still adjust the following day to account for it. Reminders continue on your set schedule.

Yes. In Advanced mode, the left panel beside the syringe shows every compound due today in a single scrollable list — TRT and all ancillaries together. Tap any card to jump straight to that compound's widget.

The syringe shows your exact draw volume in real time. As you adjust your dose, the fill level updates. Swipe to select your syringe size, then use the −/+ buttons to fine-tune your volume without opening any settings.

0.5 mL, 1 mL standard, 1 mL insulin, 3 mL, and 5 mL. Swipe to select whichever matches what you're using.

Yes — in Advanced mode. Tap the mini syringe icon on each compound card to add it to the draw. The total volume below the syringe updates to reflect the combined pull, shown as total mL and total mg.

Swipe the syringe left or right. If your testosterone is configured as a cream, the syringe automatically switches to the Topi-CLICK® dispenser view.

Classic mode shows a focused TRT configuration — concentration, frequency, and weekly dose in a clean card layout beside the syringe. Advanced mode unlocks the full daily dashboard, compound plotter charts, injection stacking, and inventory management for enhanced protocols running multiple compounds.

Men on a straightforward TRT protocol who want to manage their testosterone quickly without the complexity of multi-compound tracking. The essentials, nothing more.

Anyone running ancillaries, peptides, or enhanced protocols alongside their TRT. Advanced mode is built for compound stacking, cycle planning, and full protocol visibility across everything you're running.

Yes. The layers icon in the top right toggles between modes instantly. All your data is preserved.

Your weekly total stays locked. Only the per-injection volume adjusts. Move from twice weekly to every other day and the app automatically recalculates how much to draw each time — same total weekly dose, more frequent smaller injections.

Yes. Enter mL and the mg updates. Enter mg and the mL updates. Enter your weekly dose and both update. All fields are fully bidirectional.

The T Fluctuation percentage — shown as ∆ on the chart — is the hero metric of TRT Plus. It quantifies your complete peak-to-trough hormonal swing as a single number: how far your testosterone rises from its lowest point to its highest within a single dosing cycle.

Peak-to-trough fluctuation (PTF) is the percentage swing between your lowest testosterone level — the trough just before your next injection — and your peak shortly after. Large swings correlate with side effect variability: the energy crashes, mood dips, and libido drops some men feel toward the end of a cycle. A smaller PTF means more stable levels and typically fewer symptoms.

Same total weekly dose, more frequent smaller injections means narrower peaks and higher troughs — the hormonal swing compresses significantly. Twice-weekly dosing produces roughly 50% PTF. Every other day drops to around 22%. Daily sits at around 7.6%. The chart makes this visible before you commit to a protocol change.

Many men report fewer side effects below 35%. Every other day or three times per week are the most practical targets for most protocols. Once-weekly dosing sits around 96% — a significant swing that many men feel, even if their average levels look fine on paper.

The calculation models exponential decay and dose superposition across your injection schedule — simulating how each dose stacks on residual testosterone from previous injections at steady state. The full pharmacokinetic framework is documented in-app under My Protocol › Testosterone Fluctuation.

A pharmacokinetic chart for each compound in your protocol, showing how drug levels behave over time — when they peak, when steady state is reached, and when the compound has substantially cleared. Available in Advanced mode.

Up to 10 compounds alongside your TRT, each with its own independent chart and pharmacokinetic profile.

Steady state is the equilibrium point where the amount administered each dose equals the amount eliminated between doses — reached at approximately 5 half-lives from your first injection. Levels are still rising before this point. Bloodwork taken before steady state will underestimate your true levels.

The point at which approximately 97% of the compound has cleared your system — 5 half-lives from your most recent dose. Useful for PCT timing and washout planning. This marker is not an indicator of detection windows for drug testing purposes.

Yes. Configure a compound, set your intended start date, and the chart projects your full pharmacokinetic curve — peaks, steady state, and clearance — before you've taken a single dose.

Yes. The plotter uses route-specific pharmacokinetic models for oil-based esters, aqueous suspensions, orals, peptides, and transdermal cream — each modelled differently based on its absorption and elimination characteristics.

Bro notation is the shorthand the TRT and enhanced athlete community uses to communicate protocols — e.g. "500mg/W Test E (E3D), 400mg/W Deca (2xW), 50mg/day Anavar." TRT Plus generates a clean summary in this format automatically from your configured protocol.

Yes. Tap the share icon in the top right of My Protocol to export your protocol summary.

Up to 8 sites in sequence. Enter them counter-clockwise following the arrow direction in the planner. Unused slots are marked as N/A.

Delts, ventroglutes, glutes, lats, quads, and abdomen — left and right for bilateral sites. Each site in the Rotation Planner includes injection guidance, anatomy notes, and technique tips.

Abbreviated along the bottom of the chart, one per scheduled injection date — RD for Right Delt, LV for Left Ventroglute, RG for Right Glute, and so on.

Yes. Mark as taken or snooze directly from your smart watch without opening the app.

Yes. Each compound has its own independently scheduled reminder based on its frequency and your last dose date. Reminders fire when each compound is due.

The inventory counter turns amber at four weeks remaining and red at two weeks. Push notifications fire in advance so you're never caught short on a refill.

Yes. Inventory calculates expected usage against your dosing schedule. If a dose goes unmarked, inventory still adjusts the following day to account for it.

Yes. Peptides are fully integrated — scheduling, dose calculation, reminders, compound plotter charts, and inventory all work the same as injectables. The key difference at setup is reconstitution: peptides come as lyophilized powder and need to be mixed with bacteriostatic water before use. The app handles this with a built-in calculator.

When you add a peptide via Quick Add, the app opens a Reconstitution Calculator. Enter your vial's dry powder amount and the volume of bacteriostatic water — concentration is calculated and saved automatically. All three fields are interlinked: change any one and the others update to stay consistent. You can also set a desired concentration and the bac water volume calculates accordingly.

Yes. Up to 10 compounds run alongside your TRT simultaneously, each with independent scheduling, reminders, and inventory tracking.

All the mainstream ones — hCG, GH, BPC-157, and 31 more. If a specific peptide isn't listed, you can add it manually as a custom compound. Or email support@trtplus.app and we'll look at adding it to the library for the wider community.

Yes. Peptide doses are typically prescribed in mcg while draw volume is in mL. Once you've set your concentration in mcg/mL, the app calculates exactly how many mL to draw for your prescribed dose — and updates automatically if you adjust either field.

Yes. Testosterone cream is fully supported with its own dosing interface, application site selector, absorbed dose calculator, pharmacokinetic chart, reminders, and inventory tracking.

When you select a cream formulation, the syringe swipes to a Topi-CLICK® dispenser interface showing clicks rather than mL. The −/+ buttons adjust your click count and the mg updates automatically based on your concentration.

Below your application site selector, the app displays your absorbed dose expressed as an injectable mg/W equivalent — the same convention used across the TRT community when discussing weekly doses. This lets you directly compare your cream protocol to an injectable one, or communicate your protocol to a healthcare professional in familiar terms.

Yes, significantly. Different skin sites absorb at very different rates. Scrotal skin absorbs at roughly 55% nominal — several times higher than abdominal skin at around 8%. Select your site and the calculation updates automatically using a Michaelis-Menten saturation model calibrated per site.

Skin absorption is non-linear. Transport proteins and follicular channels saturate — at higher doses, a smaller proportion of what you apply actually reaches circulation. The app models this correctly, so the effective absorption rate shown always reflects your actual dose, not a flat nominal percentage. Doubling what you apply will always deliver less than double to your bloodstream.

Yes. The app supports daily application — the pharmacokinetically correct dosing interval for testosterone cream given its 12-hour half-life. Consistent daily dosing brings levels to steady state within two to three days and maintains them predictably from there.

Upload a photo or screenshot of your blood panel. OCR automatically extracts every marker, unit, and collection date — zero manual entry. Markers are scored against enhanced TRT-calibrated reference ranges, and a composite Biomarker Score reads the relationships between markers and key hormone ratios. The AI report then interprets your results alongside your active protocol across eight sections.

A weighted composite score that converts your individual marker results into a single overall reading. It's not a simple average — it's an algorithm that accounts for the relative importance of each marker to TRT optimization, the relationships between markers, and your personal profile. It gives you an at-a-glance assessment of how dialled in you are on your current protocol, expressed as a red, amber, green breakdown.

Take a photo or screenshot of your results — from your lab's patient portal, a PDF, or a printed report — and upload from within the app. OCR handles the extraction automatically. All values are shown for review so you can correct anything before the analysis runs.

OCR accuracy is high but not infallible — unusual formatting, low image quality, or handwritten values can occasionally cause extraction errors. Every extracted value is presented for review, so nothing gets scored incorrectly without you seeing it first.

The Biomarker Score covers 15 key TRT and performance-related markers — the most clinically important across hormones, cardiovascular health, liver, kidney, haematology, and metabolic function. All 15 are displayed in a dashboard-style red, amber, green breakdown on a single screen, so you can see your full picture at a glance.

No. All data is stored locally on your device. There are no accounts, no sign-ups, and no servers. Your bloodwork never leaves your phone.

Standard lab reference ranges are built from population studies that include sedentary men, older men, and men with suboptimal health — the full bell curve of normal. For a man on TRT optimizing for performance and wellbeing, that bar is far too low. TRT Plus uses enhanced reference ranges calibrated for optimization, not statistical normality.

They answer the wrong question. A lab range tells you whether you're within the bounds of the general population. TRT Plus asks whether you're optimized. A testosterone result that falls within the normal lab range may still represent undertreatment for a man on TRT — and an estradiol your lab flags as elevated may be exactly where it should be alongside optimized testosterone. TRT Plus considers the ratio between hormones, not any single number in isolation. The general population is not your peer group.

The ranges are built on real-world de-identified data from a clinical population of healthy, active men on TRT — HIPAA-compliant, encrypted, and secure. Your reference group matters. Standard lab ranges are built from whoever walks through the door at a pathology collection centre — an average that includes sedentary, insulin-resistant, and metabolically unhealthy people. Comparing yourself to that pool is like using a Walmart crowd as your health benchmark. TRT Plus compares you to men who train, optimize their hormones, and actively manage their health. That's a meaningfully different bar. The relationships between markers are mapped in the Engine schematic.

The algorithm that converts your individual marker values into the red, amber, green breakdown and overall Biomarker Score. It's not a flat pass/fail against a single threshold — it's a weighted system that accounts for marker relationships, your personal cardiovascular and metabolic profile, and the clinical significance of each result in the context of TRT.

Because in TRT, the right testosterone level isn't a fixed number — it's shaped by your individual health profile. TRT Plus determines your range through the Cardio-Metabolic Cascade, a framework that analyses your cardiovascular and metabolic markers together and cascades them into your personalised scoring threshold. The healthier your profile across the full cascade — markers like ApoB, blood pressure, CRP, HbA1c, and body fat, for example — the wider the range. The more deterioration, the tighter it gets.

Through the Cardio-Metabolic Cascade — a TRT Plus framework that feeds your cardiovascular and metabolic markers into your testosterone threshold in sequence, each building on the last. Rather than applying a single cutoff, the cascade treats your health as a composite picture. Improvements across the cascade widen your optimal range. Deterioration narrows it. The relationships between markers are mapped in the Engine schematic.

Hematocrit is one of the most important safety markers on TRT — elevated levels increase blood viscosity and cardiovascular risk. Rather than applying a flat threshold, the Hematocrit Scoring Engine uses the same Cardio-Metabolic Cascade logic to determine your personal ceiling. Your acceptable hematocrit threshold is modulated by your full cardiovascular and metabolic profile — making it personal rather than generic.

The report interprets your bloodwork and active protocol together, providing personalised recommendations for lifestyle, supplements, and medicinal options for areas of concern — guided by current TRT and hormone optimization best practices.

Recommendations, Hormonal Balance, Muscle-Building Potential, Dose Response, Compound Analysis, Healthspan Assessment, Cardiovascular Risk Profile, and Overall Health.

Both. Each section interprets what your results mean in context, then provides actionable recommendations — specific lifestyle modifications, supplement strategies, and medicinal options where relevant. It doesn't just tell you something is red. It tells you what to do about it.

Personalised. The AI interprets your bloodwork alongside your active protocol — the compounds you're running, your doses, and your frequency. Two people with identical bloodwork on different protocols will receive different reports.

Responder Type classifies how your body converts your testosterone dose into circulating levels — whether you're a normal, low, hyper, super, or non-responder. It tells you whether your protocol is likely to be efficient or whether you may need more or less testosterone than average to reach target levels. Understanding your responder type is essential context before adjusting dose.

An interpretation of the key ratios between your hormones — primarily testosterone to estradiol and testosterone to SHBG — to assess whether your androgenic and estrogenic environment is optimised for performance, wellbeing, and safety.

The T:E ratio is the relationship between your total testosterone and estradiol. It reflects your androgenic-to-estrogenic balance — too low suggests relative estrogen dominance, too high suggests insufficient aromatization or over-suppression. The goal on TRT isn't simply to maximize testosterone or minimize estradiol, but to maintain a ratio that supports the outcomes you're optimizing for.

The A:E ratio — Androgenic to Estrogenic — is a TRT Plus-pioneered metric that measures the balance between your total androgenic load and estradiol. Where the T:E ratio uses raw testosterone as the androgenic side, the A:E ratio uses androgenic load — a DHT-adjusted figure that accounts for the fact that DHT is a significantly more potent androgen than testosterone and a direct downstream product of it. Without factoring in DHT, raw testosterone alone understates your true androgenic environment. The A:E ratio corrects for this, giving a more complete and accurate read of your hormonal balance — and the E2 Scoring Engine is built on it.

The T:SHBG ratio assesses how your testosterone levels relate to your sex hormone-binding globulin. High SHBG binds more testosterone, reducing free availability regardless of how high your total is. The T:SHBG ratio flags whether your protocol is delivering enough bioavailable testosterone relative to your binding protein levels — a common issue that total testosterone alone won't reveal.

An assessment of your hormonal environment's capacity for muscle protein synthesis and anabolism, based on key markers including testosterone, IGF-1, and estradiol. Estradiol is often overlooked in this context — it acts as a mediator in the liver's conversion of growth hormone to IGF-1, making it a direct contributor to anabolic potential rather than simply an estrogenic marker to be managed. Muscle Building Potential contextualises your current protocol in terms of anabolic capacity — not individual hormone levels in isolation.

Yes — using four methods: Vermeulen, Mazer, Södergård, and Zakharov. Free T is derived from Total T, SHBG, and Albumin.

For reference completeness. In practice, only two matter — Vermeulen and Zakharov. The others are included so you can see how the methods compare, but they're not where your attention should be.

If you're on a standard TRT dose, Vermeulen and Zakharov will give similar results — both are valid. At the higher testosterone levels used by enhanced athletes, Zakharov is more accurate. Vermeulen was validated against physiological testosterone ranges and loses reliability at supra-physiological levels. Zakharov was designed to account for this. If you're running an enhanced protocol, Zakharov is your number.

Most labs that report Free Testosterone are calculating it from Total T and SHBG using the Vermeulen equation. True direct measurement via equilibrium dialysis exists but requires a specialist reference lab and must be specifically requested. The meaningful difference for most men on TRT isn't calculated versus measured — it's which calculation method is used.

Sex hormone-binding globulin binds tightly to testosterone in your bloodstream, making it biologically inactive. Only unbound testosterone — Free T — can enter cells and exert androgenic effects. Two men with identical Total T can have dramatically different Free T if their SHBG differs. High SHBG is common in certain men on TRT and explains suboptimal symptoms despite apparently adequate total testosterone levels.

Both measure testosterone availability — how much is actually reaching your cells rather than sitting locked to binding proteins. Free T gives you an absolute number. The T:SHBG ratio gives you a proportional read and is more intuitive for ongoing monitoring — it's displayed as a gauge in the app, changes are immediately readable, and it doesn't require albumin as an input. For most men on TRT the ratio gauge is the faster daily reference. The Free T calculation is the deeper dive when you need the full picture.

The Testimator predicts your testosterone levels under different protocols before you run them. It's anchored to your own historical bloodwork rather than population averages, so the prediction reflects your individual response — not what happens to the average man.

It uses your actual historical Total T results from previous bloodwork as the anchor point, then models how changes to dose, frequency, or ester would affect your levels based on your demonstrated personal response. The reference ranges are also dynamically adjusted based on your Biomarker Score.

Your own results. Most predictive tools use population averages — the prediction is for the average man, not you. The Testimator uses your real bloodwork as its anchor, making it meaningfully more accurate for your specific physiology.

The target range shown in the Testimator shifts based on your cardiovascular and metabolic health — consistent with the personalised reference range logic used throughout the app. A cleaner health profile earns a wider target range. Deteriorating markers narrow it. Your target range evolves as your health does.

More accurate than population-based predictors because it's personal. We regularly hear from users that the Testimator predicted their actual bloodwork results within a few ng/dL of their real result — closer than most expected from a modelling tool. It is not a clinical measurement — always verify with bloodwork after any protocol change, and consult your healthcare provider before making medical decisions.

ApoB (Apolipoprotein B) is a more direct measure of cardiovascular risk. Each atherogenic particle — regardless of how much cholesterol it carries — contains exactly one ApoB molecule. This means ApoB counts the actual number of particles that can embed in arterial walls, rather than estimating risk from their cholesterol content. LDL can appear normal while ApoB is elevated, particularly in men with small dense LDL particles — which are common with anabolic compound use. ApoB catches what LDL misses.

Standard eGFR is calculated from creatinine — a muscle metabolism byproduct. In athletes and men on TRT with above-average muscle mass, creatinine is naturally elevated, making eGFR appear artificially low and falsely suggesting impaired kidney function. Cystatin C is produced at a constant rate by all cells regardless of muscle mass, making it a far more accurate kidney function marker for this population.

AST and ALT are liver enzymes, but they're also released by muscle tissue during intense training. In men who train hard, elevated AST/ALT can reflect muscle breakdown rather than liver stress — making them unreliable for assessing hepatotoxicity from oral compounds. GGT is liver-specific and doesn't respond to muscle damage, giving a cleaner signal for hepatic stress in athletes.

Yes — region dependent. TRT Plus partners with pathology labs that use markers built for athletes: ApoB over HDL/LDL, Cystatin C over eGFR, GGT over AST/ALT. Two panels are available: Essential for everyday TRT optimization, Comprehensive for athletes and enhanced protocols.

Essential covers the core markers needed for routine TRT monitoring and optimization. Comprehensive adds the depth required for enhanced athletes — broader cardiovascular markers, advanced hormonal panels, and metabolic markers relevant to compound use. If you're running anything beyond a straightforward TRT protocol, Comprehensive is the appropriate choice.

Yes. The app lists every marker required for both the Essential and Comprehensive panels. If you prefer to order through your own lab or healthcare provider, you can use this list to request the exact markers — the full bloodwork analysis features work with results from any source.

Availability is region dependent. The app surfaces the appropriate provider for your region automatically. If no partner is available in your region, all bloodwork analysis features still work in full with results from your own lab.

Yes. Upload a photo or screenshot of any bloodwork result and OCR extracts your values automatically. The full Biomarker Score, AI report, and all analysis features work with results from any lab anywhere in the world. The pathology partner integration is an additional option, not a requirement.

Yes. Tap any marker heading to instantly convert between all standard international units. Most TRT content online — podcasts, forums, research — references US units: ng/dL for testosterone and pg/mL for estradiol. If your results are in nmol/L or pmol/L, a single tap converts them so you can follow along without doing the mental arithmetic every time.

Trough is the standard — blood drawn immediately before your next dose, whether that's before an injection or before your daily cream application. This is the lowest point of your cycle and gives your healthcare provider the most consistent baseline for monitoring. The Compound Plotter shows exactly when trough occurs for your specific protocol.

Steady state is reached at approximately five half-lives from starting or changing your protocol — the point at which drug levels have stabilised and are no longer rising. Testing before steady state underestimates your true levels and can lead to premature dose adjustments. For Test E or Test Cyp, steady state is around four weeks. For longer esters like Nebido, it's closer to fifteen weeks. The Compound Plotter marks steady state on your chart so you always know when you're ready to test.

Yes. Bloodwork reminders are set from your last results and calibrated to TRT best practice retesting intervals — the app tells you when it's time to test again rather than leaving you to figure it out.

Retesting intervals are calculated from your last bloodwork date in line with TRT monitoring guidelines. Any protocol change warrants bloodwork after reaching steady state — the app accounts for this rather than applying a flat calendar interval.